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Leoni A Kunz-Schughart Selected Research

Canavanine

3/2021Dual role of ER stress in response to metabolic co-targeting and radiosensitivity in head and neck cancer cells.
5/2012Single amino acid arginine starvation efficiently sensitizes cancer cells to canavanine treatment and irradiation.

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Leoni A Kunz-Schughart Research Topics

Disease

56Neoplasms (Cancer)
03/2022 - 11/2002
11Carcinoma (Carcinomatosis)
12/2021 - 06/2003
9Colorectal Neoplasms (Colorectal Cancer)
03/2021 - 09/2009
5Starvation
01/2021 - 05/2012
5Glioblastoma (Glioblastoma Multiforme)
12/2019 - 03/2006
4Squamous Cell Carcinoma of Head and Neck
03/2022 - 01/2016
4Neoplasm Metastasis (Metastasis)
08/2011 - 06/2003
3Prostatic Neoplasms (Prostate Cancer)
01/2021 - 04/2015
3Glioma (Gliomas)
12/2019 - 12/2004
3Tics (Tic)
01/2016 - 09/2009
3Hypoxia (Hypoxemia)
01/2016 - 02/2011
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
08/2014 - 01/2013
3Melanoma (Melanoma, Malignant)
01/2009 - 12/2004
2Hyperthermia
06/2021 - 01/2021
2Head and Neck Neoplasms (Head and Neck Cancer)
01/2016 - 08/2014
1Pancreatic Neoplasms (Pancreatic Cancer)
12/2021
1T-Cell Leukemia (Leukemia, T Cell)
12/2021
1Burkitt Lymphoma (Burkitt's Lymphoma)
12/2021
1Metabolic Diseases (Metabolic Disease)
01/2017
1Whooping Cough (Pertussis)
09/2010
1Cholera
09/2010
1Acidosis
11/2009

Drug/Important Bio-Agent (IBA)

10Proteins (Proteins, Gene)FDA Link
03/2022 - 01/2003
9Arginine (L-Arginine)FDA Link
03/2021 - 05/2012
7Pharmaceutical PreparationsIBA
12/2013 - 06/2004
7Lactic Acid (Lactate)FDA LinkGeneric
08/2011 - 06/2003
6Biomarkers (Surrogate Marker)IBA
01/2021 - 12/2004
5Amino AcidsFDA Link
01/2021 - 05/2012
3Messenger RNA (mRNA)IBA
03/2022 - 11/2002
3Biological ProductsIBA
01/2017 - 07/2007
2CanavanineIBA
03/2021 - 05/2012
2ArginaseIBA
03/2021 - 05/2012
2Aldehyde DehydrogenaseIBA
01/2021 - 04/2015
2SuspensionsIBA
01/2020 - 10/2002
2Methionine (L-Methionine)FDA Link
01/2017 - 11/2013
2CitrullineIBA
11/2016 - 11/2013
2AntibodiesIBA
01/2016 - 03/2006
2Cetuximab (Erbitux)FDA Link
08/2014 - 01/2013
2ErbB Receptors (EGF Receptor)IBA
08/2014 - 01/2013
2EnzymesIBA
05/2012 - 02/2011
2CytokinesIBA
08/2011 - 03/2006
2Calcibiotic Root Canal SealerIBA
03/2010 - 09/2009
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2009 - 08/2005
2PPAR gammaIBA
01/2009 - 03/2007
2Transforming Growth Factor beta1 (TGF beta 1)IBA
07/2007 - 03/2006
2Conditioned Culture MediaIBA
03/2006 - 05/2003
2Interleukin-6 (Interleukin 6)IBA
03/2006 - 05/2003
1Chimeric Antigen ReceptorsIBA
03/2022
1Heavy Chain Fusion Regulatory Protein 1IBA
03/2022
1ProdrugsIBA
12/2021
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2021
1Membrane Proteins (Integral Membrane Proteins)IBA
03/2021
1indospicineIBA
03/2021
1TOR Serine-Threonine KinasesIBA
03/2021
1Glutamine (L-Glutamine)FDA Link
01/2021
1Surface Antigens (Surface Antigen)IBA
01/2020
1Tricarboxylic AcidsIBA
12/2019
1Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
12/2019
1NADP (NADPH)IBA
12/2019
1Small Interfering RNA (siRNA)IBA
01/2019
1Essential Amino AcidsIBA
01/2017
1AsparagineIBA
01/2017
1Argininosuccinate Synthase (Argininosuccinate Synthetase)IBA
11/2016
1Tumor Suppressor Protein p53IBA
02/2016
1Antimalarials (Antimalarial Agents)IBA
01/2016
1UbiquinoneIBA
01/2016
1Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA
01/2016
1Integrin beta1IBA
01/2016
1Atovaquone (Mepron)FDA Link
01/2016
1IntegrinsIBA
01/2016
1CateninsIBA
04/2015
1Radioisotopes (Radionuclides)IBA
08/2014
1Leucine (L-Leucine)FDA Link
11/2013
1Lysine (L-Lysine)FDA Link
11/2013
1Polo-Like Kinase 1IBA
09/2013
1BI 6727IBA
09/2013
1AC133 AntigenIBA
02/2013
1EpitopesIBA
02/2013
1A-factor (Streptomyces)IBA
05/2012
1Pyruvic Acid (Pyruvate)IBA
08/2011
1Irinotecan (Camptosar)FDA LinkGeneric
02/2011
1baysilon (polydimethylsiloxane)IBA
02/2011
12,4-thiazolidinedione (thiazolidinedione)IBA
01/2011
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
01/2011
1PPAR-gamma AgonistsIBA
01/2011
1Pioglitazone (Actos)FDA Link
01/2011
1CCR2 ReceptorsIBA
09/2010
1Pertussis ToxinIBA
09/2010
1Oxamic AcidIBA
02/2010
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
02/2010

Therapy/Procedure

21Therapeutics
03/2021 - 11/2002
10Radiotherapy
06/2021 - 04/2012
3Drug Therapy (Chemotherapy)
01/2009 - 03/2007
2Chemoradiotherapy
03/2022 - 01/2019
1Immunotherapy
03/2022
1Proton Therapy
08/2021
1Induced Hyperthermia (Thermotherapy)
06/2021
1Precision Medicine
01/2020
1Aftercare (After-Treatment)
01/2016
1Lasers (Laser)
04/2011